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However, the efficiency of BBB crossing in humans is not precisely known

Based on the functional enrichment analysis of the differentially expressed proteins, we observed significant enrichment changes in several key biological processes and cellular structural components in the si-PGC-1 LNP-treated T24 cell line

Resveratrol prevents renal lipotoxicity and inhibits mesangial cell glucotoxicity in a manner dependent on the AMPK-SIRT1-PGC1 axis in db/db mice

For instance, studies in laboratory rodents have found that dietary omega-3 PUFA deficiency impaired measures of cognitive performance through influencing the dopamine neurotransmitter system in the frontal cortex region of the brain (98)

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